Snake Oil...

Image Source: Link below

Topics: Biology, DNA, Genetics

"Extraordinary claims require extraordinary evidence." Carl Sagan

I'm guessing "I did Ancestry" is going to become the "I used to do Amway" in the 21st Century?

I participated, thinking it was legitimate science. It did somewhat jive with my own experiences of being consistently identified by Nigerians as resembling someone from the Igbo. This again is pure conjecture, and likely only a polite guess.

I can see the desire to know about our roots, especially if you're a part of the African Diaspora is tempting as well as an opportunity for confidence rackets and quackery.

In the spring of 2017, a college student named Mary spit into a tube and sent it to the DNA testing company Ancestry, which analyzed it and sent back a breakdown of her family history.

But Mary wanted to know more. The human genome contains, in theory, an extraordinary wealth of pre-programmed information about who we are and who we might become: whether she was at risk for the same types of cancer that killed her parents, for instance, or if she had medical conditions she could unknowingly pass on to her children.

For that information, Mary — we’re withholding her last name to protect her privacy — turned to a dubious new sector of the genomics industry, in which startups claim to provide vastly greater insights than prominent companies like Ancestry and 23andMe do. She uploaded a copy of her raw genetic code, which Ancestry provided as a 17.6 megabyte text file, to a site called Genomelink, which advertises tests for everything from medical conditions and mental illnesses to ludicrously specific personality traits including “loneliness,” “social communication problems,” and “vulnerability to helicopter parenting.”

But when her results arrived, Mary immediately noticed that many were “wildly inaccurate.” Genomelink said she was “less easily depressed,” but Mary was diagnosed with clinical depression at a young age. The startup predicted that she had a peanut allergy, but Mary told Futurism that “peanut butter is one of the true loves of my life.” Other errors in Mary’s report included traits like blood iron levels, body fat measurements, hearing problems, height, and skin complexion.

“I felt that much of it was off-base and unhelpful,” she told Futurism, “as it didn’t fit me at all.”

Genomelink is just one of a growing number of shady DNA testing startups now operating in the regulatory Wild West of commercial genomics.

There’s GenePlaza, for instance, which sold a DNA test that claimed to predict users’ sexual preferences — and still sells tests that purport to measure intelligence and risk of depression. A company called Soccer Genomics claims to examine a child’s DNA to create a sports training regimen to turn them into the perfect soccer player. An outfit called GenoPalate told a Milwaukee Journal Sentinel reporter that their DNA demanded a diet of elk meat and passion fruit. A venture called Vinome claims it can recommend the perfect wine for each person based on their genetic code.

The problem, according to experts, is that these companies are promising information about DNA with a granularity that even scientists can’t deliver. Deanna Church, a geneticist at the biotech company Inscripta, told Futurism the tests are “all equally useless.”

“There is not a scientific basis for this sort of testing,” she said. “I certainly would not recommend anyone spend any money on this sort of thing.”

"Like Horoscope Readings!": The Scammy World of DNA Startups, Dan Robitzki, Futurism